On June 7, 2008, Paul Williams and Carlos Quintana met again in an immediate rematch.
Williams came in to the fight on a 1-fight losing streak with a 70% KO rate, and was fighting after a gap of 3 months and 29 days. Quintana was on a 2-fight win streak with a 73% KO rate, and fighting after a layoff of 3 months and 29 days.
Paul Williams made quick work of Carlos Quintana in the rematch, stopping the champion via TKO in the 1st. Williams improves his record to 34-1 (25 KOs), while Quintana adds a loss to his record at 25-2.
On July 14, 2007, a 25-year-old Paul Williams (32-0, 24 KOs) got a shot at the WBO welterweight title held by 29-year-old Mexican boxer Antonio Margarito (34-4, 24 KOs).
Williams came in to the fight on a 32-fight win streak with a 75% KO rate, and was fighting after a gap of 8 months and 10 days. Margarito was on a 4-fight win streak with a 63% KO rate, and fighting after a layoff of 7 months and 12 days.
Paul Williams defeated Antonio Margarito via unanimous decision and wins the WBO title — in his first world-title fight. Williams improves his record to 33-0, while Margarito adds a loss to his record at 34-5.
On November 29, 2008, a 27-year-old Paul Williams (35-1, 26 KOs) and Verno Phillips met in the ring in a super-welterweight bout.
Williams came in to the fight on a 2-fight win streak with a 72% KO rate, and was fighting after a gap of 2 months and 4 days.
Paul Williams stopped Verno Phillips via TKO in the 8th round. Williams improves his record to 36-1 (27 KOs)
On August 19, 2006, a 25-year-old Paul Williams (30-0, 22 KOs) and a 35-year-old Sharmba Mitchell (57-5, 30 KOs) met in the ring in a welterweight bout.
Williams came in to the fight on a 30-fight win streak with a 73% KO rate, and was fighting after a gap of 2 months and 23 days. Mitchell was on a 1-fight win streak with a 48% KO rate, and fighting after a layoff of 3 months and 16 days.
Paul Williams stopped Sharmba Mitchell via KO in the 4th round. Williams improves his record to 31-0 (23 KOs), while Mitchell adds a loss to his record at 57-6.
On September 25, 2008, a 27-year-old Paul Williams (34-1, 25 KOs) and Andy Kolle met in the ring.
Williams came in to the fight on a 1-fight win streak with a 71% KO rate, and was fighting after a gap of 3 months and 18 days.
Paul Williams stopped Andy Kolle via TKO in the 1st round. Williams improves his record to 35-1 (26 KOs)
On May 27, 2006, a 24-year-old Paul Williams (29-0, 21 KOs) and Walter Matthysse met in the ring in a welterweight bout.
Williams came in to the fight on a 29-fight win streak with a 72% KO rate, and was fighting after a gap of 1 month and 15 days.
Paul Williams stopped Walter Matthysse via TKO in the 10th round. Williams improves his record to 30-0 (22 KOs)
On December 5, 2009, a 28-year-old Paul Williams (37-1, 27 KOs) and a 34-year-old Argentinian boxer Sergio Martínez (44-1-2, 24 KOs) met in the ring.
Williams came in to the fight on a 4-fight win streak with a 71% KO rate, and was fighting after a gap of 7 months and 24 days. Martínez was on a 0-fight win streak with a 51% KO rate, and fighting after a layoff of 9 months and 21 days.
Paul Williams defeated Sergio Martínez via majority decision in the 12-round fight. Williams improves his record to 38-1, while Martínez adds a loss to his record at 44-2-2.
On February 18, 2012, a 30-year-old Paul Williams (40-2, 27 KOs) and a 36-year-old Japanese boxer Nobuhiro Ishida (24-6-2, 9 KOs) met in the ring.
Williams came in to the fight on a 1-fight win streak with a 64% KO rate, and was fighting after a gap of 7 months and 9 days. Ishida was on a 2-fight win streak with a 28% KO rate, and fighting after a layoff of 2 months and 23 days.
Paul Williams defeated Nobuhiro Ishida via unanimous decision in the 12-round fight. Williams improves his record to 41-2, while Ishida adds a loss to his record at 24-7-2.
On February 9, 2008, the 26-year-old WBO welterweight world champion, Paul Williams (33-0, 24 KOs), faced a 31-year-old Puerto Rican boxer Carlos Quintana (24-1, 19 KOs), in a title defense fight.
Williams came in to the fight on a 33-fight win streak with a 72% KO rate, and was fighting after a gap of 6 months and 26 days. Quintana was on a 1-fight win streak with a 76% KO rate, and fighting after a layoff of 4 months and 11 days.
Carlos Quintana defeated Paul Williams via unanimous decision and wins the WBO title — in his first world-title fight. Quintana improves his record to 25-1, while Williams adds a loss to his record at 33-1.
On September 23, 2004, a 23-year-old Paul Williams (23-0, 17 KOs) and Javier Hector Valadez met in the ring.
Williams came in to the fight on a 23-fight win streak with a 73% KO rate, and was fighting after a gap of 4 months and 16 days.
Paul Williams stopped Javier Hector Valadez via TKO in the 1st round. Williams improves his record to 24-0 (18 KOs)