On August 16, 2006, a 37-year-old Keith Holmes (40-4, 25 KOs) and Tito Mendoza met in the ring in a light-heavyweight bout.
Holmes came in to the fight on a 1-fight win streak with a 56% KO rate, and was fighting after a gap of -1 months and -21 days.
Keith Holmes lost to Tito Mendoza via unanimous decision in the 8-round light-heavyweight fight, and adds an loss to his record at 40-5.
On April 2, 2005, a 36-year-old Keith Holmes (39-3, 25 KOs) and a 32-year-old Russian boxer Roman Karmazin (32-1-1, 21 KOs) met in the ring.
Holmes came in to the fight on a 3-fight win streak with a 59% KO rate, and was fighting after a gap of 1 year and 19 days. Karmazin was on a 3-fight win streak with a 60% KO rate, and fighting after a layoff of 10 months and 18 days.
Roman Karmazin defeated Keith Holmes via majority decision in the 12-round fight. Karmazin improves his record to 33-1-1, while Holmes adds a loss to his record at 39-4.
On April 14, 2001, the 32-year-old WBC middleweight world champion, Keith Holmes (36-2, 24 KOs), faced a 36-year-old Bernard Hopkins (38-2-1, 28 KOs), in a title defense fight.
Holmes came in to the fight on a 5-fight win streak with a 63% KO rate, and was fighting after a gap of 11 months and 16 days. Hopkins was on a 12-fight win streak with a 68% KO rate, and fighting after a layoff of 4 months and 13 days.
Bernard Hopkins defeated Keith Holmes via unanimous decision and unifies the WBC middleweight titles. Hopkins improves his record to 39-2-1, while Holmes adds a loss to his record at 36-3.
On May 2, 1998, the 29-year-old WBC middleweight world champion, Keith Holmes (31-1, 21 KOs), faced a 30-year-old French boxer Hacine Cherifi (24-3-1, 17 KOs), in a title defense fight.
Holmes came in to the fight on a 24-fight win streak with a 65% KO rate, and was fighting after a gap of 4 months and 27 days. Cherifi was on a -1-fight win streak with a 60% KO rate, and fighting after a layoff of 7 months and 21 days.
Hacine Cherifi defeated Keith Holmes via unanimous decision and wins the WBC title — in his first world-title fight. Cherifi improves his record to 25-3-1, while Holmes adds a loss to his record at 31-2.
On July 20, 1990, a 21-year-old Keith Holmes (7-0, 2 KOs) and Ronald Hammond met in the ring.
Holmes came in to the fight on a 7-fight win streak with a 28% KO rate, and was fighting after a gap of 1 month and 5 days.
Keith Holmes lost to Ronald Hammond via unanimous decision in the 6-round fight, and adds an loss to his record at 7-1.