On December 3, 2011, Antonio Margarito and Miguel Cotto met again in a rematch.
Margarito came in to the fight on a 1-fight losing streak with a 60% KO rate, and was fighting after a gap of 1 year and 20 days. Cotto was on a 2-fight win streak with a 76% KO rate, and fighting after a layoff of 8 months and 21 days.
In the rematch, the challenger refused to continue the fight in the 9th round, and Miguel Cotto is crowned the new super-welterweight world champion. Cotto improves his record to 37-2 (30 KOs), while Margarito adds a loss to his record at 38-8.
On November 13, 2010, 32-year-old Antonio Margarito (38-6, 27 KOs) and 31-year-old Manny Pacquiao (51-3-2, 38 KOs) fought for the vacant WBC super-welterweight title.
Margarito came in to the fight on a 1-fight win streak with a 61% KO rate, and was fighting after a gap of 6 months and 5 days. Pacquiao was on a 12-fight win streak with a 67% KO rate, and fighting after a layoff of 8 months.
Manny Pacquiao defeated Antonio Margarito via unanimous decision . Pacquiao improves his record to 52-3-2, while Margarito adds a loss to his record at 38-7.
On January 24, 2009, the 30-year-old WBA (Super) welterweight world champion, Antonio Margarito (37-5, 27 KOs), faced a 37-year-old American boxer Shane Mosley (45-5, 38 KOs), in a title defense fight.
Margarito came in to the fight on a 3-fight win streak with a 64% KO rate, and was fighting after a gap of 5 months and 29 days. Mosley was on a 1-fight win streak with a 76% KO rate, and fighting after a layoff of 3 months and 28 days.
Shane Mosley stopped the champion via TKO in the 9th round of the 12-round world-title fight, and is crowned the new WBA (Super) welterweight champion. Mosley improves his record to 46-5 (39 KOs), while Margarito adds a loss to his record at 37-6.
On July 14, 2007, the 29-year-old WBO welterweight world champion, Antonio Margarito (34-4, 24 KOs), faced a 25-year-old American boxer Paul Williams (32-0, 24 KOs), in a title defense fight.
Margarito came in to the fight on a 4-fight win streak with a 63% KO rate, and was fighting after a gap of 7 months and 12 days. Williams was on a 32-fight win streak with a 75% KO rate, and fighting after a layoff of 8 months and 10 days.
Paul Williams defeated Antonio Margarito via unanimous decision and wins the WBO title — in his first world-title fight. Williams improves his record to 33-0, while Margarito adds a loss to his record at 34-5.
On September 11, 2004, Antonio Margarito and Daniel Santos met again in a rematch.
Margarito came in to the fight on a 21-fight win streak with a 63% KO rate, and was fighting after a gap of 7 months and 11 days.
Antonio Margarito was defending his super-welterweight titles and, fighting for the super-welterweight WBO titles against Daniel Santos and lost via technical decision in the 12-round super-welterweight fight, and adds an loss to his record at 30-4.
On June 28, 1996, an 18-year-old Antonio Margarito (9-2, 5 KOs) and Rodney Jones met in the ring.
Margarito came in to the fight on a 1-fight win streak with a 45% KO rate, and was fighting after a gap of 2 months and 10 days.
Antonio Margarito lost to Rodney Jones via unanimous decision in the 10-round fight, and adds an loss to his record at 9-3.
On February 26, 1996, a 17-year-old Antonio Margarito (8-1, 4 KOs) and Larry Dixon met in the ring.
Margarito came in to the fight on a 3-fight win streak with a 44% KO rate, and was fighting after a gap of 5 months and 16 days.
Antonio Margarito lost to Larry Dixon via unanimous decision in the 10-round fight, and adds an loss to his record at 8-2.
On October 17, 1994, a 16-year-old Antonio Margarito (5-0, 3 KOs) and Victor Lozoya met in the ring.
Margarito came in to the fight on a 5-fight win streak with a 60% KO rate, and was fighting after a gap of 2 months and 12 days.
Antonio Margarito lost to Victor Lozoya via points decision in the 6-round fight, and adds an loss to his record at 5-1.