On December 19, 2020, a 36-year-old Juan Carlos Payano (21-4, 9 KOs) and a 27-year-old American boxer Gary Antonio Russell (17-0, 12 KOs) met in the ring.
Payano came in to the fight on a 2-fight losing streak with a 36% KO rate, and was fighting after a gap of 2 months and 23 days. Russell was on a 17-fight win streak with a 70% KO rate, and fighting after a layoff of 10 months and 11 days.
Gary Antonio Russell defeated Juan Carlos Payano via technical decision in the 10-round fight. Russell improves his record to 18-0, while Payano adds a loss to his record at 21-5.
On September 26, 2020, a 36-year-old Juan Carlos Payano (21-3, 9 KOs) and a 30-year-old American boxer Daniel Roman (27-3-1, 10 KOs) met in the ring.
Payano came in to the fight on a 1-fight losing streak with a 37% KO rate, and was fighting after a gap of 1 year, 2 months, and 6 days. Roman was on a -1-fight win streak with a 32% KO rate, and fighting after a layoff of 7 months and 27 days.
Daniel Roman defeated Juan Carlos Payano via unanimous decision in the 12-round fight. Roman improves his record to 28-3-1, while Payano adds a loss to his record at 21-4.
On July 20, 2019, a 35-year-old Juan Carlos Payano (21-2, 9 KOs) and a 24-year-old Mexican boxer Luis Nery (29-0, 23 KOs) met in the ring in a bantamweight bout.
Payano came in to the fight on a 1-fight win streak with a 39% KO rate, and was fighting after a gap of 4 months and 11 days. Nery was on a 29-fight win streak with a 79% KO rate, and fighting after a layoff of 4 months and 4 days.
Luis Nery stopped Juan Carlos Payano via KO in the 9th round. Nery improves his record to 30-0 (24 KOs), while Payano adds a loss to his record at 21-3.
On October 7, 2018, a 34-year-old Juan Carlos Payano (20-1, 9 KOs) got a shot at the bantamweight WBA (Regular) title held by 25-year-old Japanese boxer Naoya Inoue (16-0, 14 KOs).
Payano came in to the fight on a 3-fight win streak with a 42% KO rate, and was fighting after a gap of 6 months and 14 days. Inoue was on a 16-fight win streak with a 87% KO rate, and fighting after a layoff of 4 months and 12 days.
Naoya Inoue made quick work of Juan Carlos Payano, stopping the challenger via TKO in the 1st. Inoue improves his record to 17-0 (15 KOs), while Payano adds a loss to his record at 20-2.
On June 18, 2016, Juan Carlos Payano and Rau'shee Warren met again in an immediate rematch.
Payano came in to the fight on a 17-fight win streak with a 47% KO rate, and was fighting after a gap of 10 months and 16 days.
Juan Carlos Payano was defending his bantamweight WBA (Undisputed) titles against Rau'shee Warren and lost via majority decision in the 12-round bantamweight fight, and adds an loss to his record at 17-1.