On June 7, 2008, a 24-year-old Juan Manuel López (21-0, 19 KOs) got a shot at the WBO super-bantamweight title held by 27-year-old Mexican boxer Daniel Ponce de León (34-1, 30 KOs).
López came in to the fight on a 21-fight win streak with a 90% KO rate, and was fighting after a gap of 3 months and 15 days. León was on a 10-fight win streak with a 85% KO rate, and fighting after a layoff of 5 months and 30 days.
Juan Manuel López made quick work of Daniel Ponce de León, stopping the champion via TKO in the 1st. López improves his record to 22-0 (20 KOs), while León adds a loss to his record at 34-2.
On July 10, 2010, the 27-year-old WBO featherweight world champion, Juan Manuel López (28-0, 25 KOs), faced Bernabé Concepción, in a title defense fight.
López came in to the fight on a 28-fight win streak with a 89% KO rate, and was fighting after a gap of 5 months and 17 days.
Juan Manuel López made very easy work of Bernabé Concepción, stopping the challenger via TKO in the 2nd. López improves his record to 29-0 (26 KOs)
On November 6, 2010, the 27-year-old WBO featherweight world champion, Juan Manuel López (29-0, 26 KOs), faced a 35-year-old Mexican boxer Rafael Márquez (39-5, 35 KOs), in a title defense fight.
López came in to the fight on a 29-fight win streak with a 89% KO rate, and was fighting after a gap of 3 months and 27 days. Márquez was on a 2-fight win streak with a 79% KO rate, and fighting after a layoff of 5 months and 15 days.
The challenger refused to continue the fight in the 8th round, and Juan Manuel López is crowned the new featherweight world champion. López improves his record to 30-0 (27 KOs), while Márquez adds a loss to his record at 39-6.
On October 4, 2008, the 25-year-old WBO super-bantamweight world champion, Juan Manuel López (22-0, 20 KOs), faced Cesar Figueroa, in a title defense fight.
López came in to the fight on a 22-fight win streak with a 90% KO rate, and was fighting after a gap of 3 months and 27 days.
Juan Manuel López made quick work of Cesar Figueroa, stopping the challenger via KO in the 1st. López improves his record to 23-0 (21 KOs)
On December 6, 2008, the 25-year-old WBO super-bantamweight world champion, Juan Manuel López (23-0, 21 KOs), faced Sergio Manuel Medina, in a title defense fight.
López came in to the fight on a 23-fight win streak with a 91% KO rate, and was fighting after a gap of 2 months and 2 days.
Juan Manuel López made quick work of Sergio Manuel Medina, stopping the challenger via TKO in the 1st. López improves his record to 24-0 (22 KOs)
On March 15, 2014, a 30-year-old Juan Manuel López (33-3, 30 KOs) and a 33-year-old Mexican boxer Daniel Ponce de León (45-5, 35 KOs) met in the ring for the 2nd time, in a super-featherweight bout.
López came in to the fight on a 1-fight losing streak with a 83% KO rate, and was fighting after a gap of 9 months. León was on a 1-fight win streak with a 70% KO rate, and fighting after a layoff of 3 months and 27 days.
In the rematch, Juan Manuel López stopped Daniel Ponce de León via TKO in the 2nd round. López improves his record to 34-3 (31 KOs), while León adds a loss to his record at 45-6.
On April 25, 2009, the 25-year-old WBO super-bantamweight world champion, Juan Manuel López (24-0, 22 KOs), faced a 36-year-old Filipino boxer Gerry Peñalosa (54-6-2, 36 KOs), in a title defense fight.
López came in to the fight on a 24-fight win streak with a 91% KO rate, and was fighting after a gap of 4 months and 19 days. Peñalosa was on a 3-fight win streak with a 58% KO rate, and fighting after a layoff of 2 months and 4 days.
The challenger refused to continue the fight in the 10th round, and Juan Manuel López is crowned the new super-bantamweight world champion. López improves his record to 25-0 (23 KOs), while Peñalosa adds a loss to his record at 54-7-2.
On January 23, 2010, a 26-year-old Juan Manuel López (27-0, 24 KOs) got a shot at the WBO featherweight title held by Steven Luevano.
López came in to the fight on a 27-fight win streak with a 88% KO rate, and was fighting after a gap of 3 months and 13 days.
Juan Manuel López stopped the champion via TKO in the 7th round of the 12-round world-title fight, and is crowned the new WBO featherweight champion. López improves his record to 28-0 (25 KOs)
On June 27, 2009, the 25-year-old WBO super-bantamweight world champion, Juan Manuel López (25-0, 23 KOs), faced Olivier Lontchi, in a title defense fight.
López came in to the fight on a 25-fight win streak with a 92% KO rate, and was fighting after a gap of 2 months and 2 days.
The challenger refused to continue the fight in the 9th round, and Juan Manuel López is crowned the new super-bantamweight world champion. López improves his record to 26-0 (24 KOs)
On October 10, 2009, the 26-year-old WBO super-bantamweight world champion, Juan Manuel López (26-0, 24 KOs), faced Rogers Mtagwa, in a title defense fight.
López came in to the fight on a 26-fight win streak with a 92% KO rate, and was fighting after a gap of 3 months and 13 days.
Juan Manuel López defeated Rogers Mtagwa via unanimous decision and successfully defended his WBO super-bantamweight title. López improves his record to 27-0