On October 12, 2013, a 40-year-old Juan Manuel Márquez (55-6-1, 40 KOs) got a shot at the welterweight WBO title held by 30-year-old American boxer Timothy Bradley (30-0, 12 KOs).
Márquez came in to the fight on a 2-fight win streak with a 64% KO rate, and was fighting after a gap of 10 months and 4 days. Bradley was on a 30-fight win streak with a 40% KO rate, and fighting after a layoff of 6 months and 26 days.
Timothy Bradley defeated Juan Manuel Márquez via split decision and successfully defended his WBO welterweight title. Bradley improves his record to 31-0, while Márquez adds a loss to his record at 55-7-1.
On November 12, 2011, Juan Manuel Márquez and Manny Pacquiao met again in a rematch.
Márquez came in to the fight on a 3-fight win streak with a 66% KO rate, and was fighting after a gap of 3 months and 27 days. Pacquiao was on a 14-fight win streak with a 65% KO rate, and fighting after a layoff of 6 months and 5 days.
Manny Pacquiao defeated Juan Manuel Márquez via majority decision in the rematch and successfully defended his WBO welterweight title. Pacquiao improves his record to 54-3-2, while Márquez adds a loss to his record at 53-6-1.
On September 19, 2009, a 36-year-old Juan Manuel Márquez (50-4-1, 37 KOs) and a 32-year-old American boxer Floyd Mayweather Jr. (39-0, 25 KOs) met in the ring.
Márquez came in to the fight on a 2-fight win streak with a 67% KO rate, and was fighting after a gap of 6 months and 22 days. Mayweather Jr. was on a 39-fight win streak with a 64% KO rate, and fighting after a layoff of 1 year, 9 months, and 11 days.
Floyd Mayweather Jr. defeated Juan Manuel Márquez via unanimous decision in the 12-round fight. Mayweather Jr. improves his record to 40-0, while Márquez adds a loss to his record at 50-5-1.
On March 15, 2008, Juan Manuel Márquez and Manny Pacquiao met again in a rematch.
Márquez came in to the fight on a 4-fight win streak with a 67% KO rate, and was fighting after a gap of 4 months and 12 days. Pacquiao was on a 6-fight win streak with a 68% KO rate, and fighting after a layoff of 5 months and 9 days.
Manny Pacquiao defeated Juan Manuel Márquez via split decision in the rematch and wins the WBC and The Ring titles. Pacquiao improves his record to 46-3-2, while Márquez adds a loss to his record at 48-4-1.
On March 4, 2006, a 32-year-old Juan Manuel Márquez (44-2-1, 33 KOs) got a shot at the featherweight WBA title held by 26-year-old Indonesian boxer Chris John (36-0-1, 20 KOs).
Márquez came in to the fight on a 2-fight win streak with a 70% KO rate, and was fighting after a gap of 9 months and 25 days. John was on a 2-fight win streak with a 54% KO rate, and fighting after a layoff of 6 months and 25 days.
Chris John defeated Juan Manuel Márquez via unanimous decision and successfully defended his WBA featherweight title. John improves his record to 37-0-1, while Márquez adds a loss to his record at 44-3-1.
On September 11, 1999, a 26-year-old Juan Manuel Márquez (29-1, 22 KOs) got a shot at the featherweight WBA title held by Freddie Norwood.
Márquez came in to the fight on a 29-fight win streak with a 73% KO rate, and was fighting after a gap of 4 months and 1 day.
Juan Manuel Márquez was defending his featherweight titles and, fighting for the featherweight WBA titles against Freddie Norwood and lost via unanimous decision in the 12-round featherweight fight, and adds an loss to his record at 29-2.
On May 29, 1993, a 19-year-old Juan Manuel Márquez (debutant) and Javier Duran met in the ring.
Juan Manuel Márquez lost to Javier Duran via disqualification in the 1-round fight, making an unsuccessful professional debut.