On April 26, 2019, Juan Francisco Estrada and Srisaket Sor Rungvisai met again in a rematch.
Estrada came in to the fight on a 2-fight win streak with a 63% KO rate, and was fighting after a gap of 4 months and 18 days. Rungvisai was on a 20-fight win streak with a 78% KO rate, and fighting after a layoff of 6 months and 20 days.
Juan Francisco Estrada defeated Srisaket Sor Rungvisai via unanimous decision in the rematch and wins the WBC and The Ring titles. Estrada improves his record to 39-3, while Rungvisai adds a loss to his record at 47-5-1.
On March 13, 2021, Juan Francisco Estrada and Román González met again in a rematch.
Estrada came in to the fight on a 5-fight win streak with a 63% KO rate, and was fighting after a gap of 4 months and 18 days. González was on a 4-fight win streak with a 78% KO rate, and fighting after a layoff of 4 months and 18 days.
Juan Francisco Estrada defeated Román González via split decision in the rematch and unifies the WBC, The Ring, and WBA (Super) super-flyweight titles. Estrada improves his record to 42-3, while González adds a loss to his record at 50-3.
On March 28, 2015, the 24-year-old WBA (Unified) and WBO flyweight world champion, Juan Francisco Estrada (31-2, 22 KOs), faced Rommel Asenjo, in a title defense fight.
Estrada came in to the fight on a 5-fight win streak with a 66% KO rate, and was fighting after a gap of 3 months and 22 days.
Juan Francisco Estrada made easy work of Rommel Asenjo, stopping the challenger via TKO in the 3rd. Estrada improves his record to 32-2 (23 KOs)
On July 27, 2013, the 23-year-old WBA (Unified) and WBO flyweight world champion, Juan Francisco Estrada (27-2, 20 KOs), faced a 25-year-old Filipino boxer Milan Melindo (29-0, 12 KOs), in a title defense fight.
Estrada came in to the fight on a 1-fight win streak with a 69% KO rate, and was fighting after a gap of 3 months and 21 days. Melindo was on a 29-fight win streak with a 41% KO rate, and fighting after a layoff of 3 months and 21 days.
Juan Francisco Estrada defeated Milan Melindo via unanimous decision and successfully defended his WBA (Unified) and WBO flyweight titles. Estrada improves his record to 28-2, while Melindo adds a loss to his record at 29-1.
On December 3, 2022, Juan Francisco Estrada and Román González met again in a rematch.
Estrada came in to the fight on a 7-fight win streak with a 60% KO rate, and was fighting after a gap of 3 months. González was on a 1-fight win streak with a 75% KO rate, and fighting after a layoff of 8 months and 28 days.
Juan Francisco Estrada defeated Román González via majority decision in the rematch and successfully defended his The Ring super-flyweight title. Estrada improves his record to 44-3, while González adds a loss to his record at 51-4.
On April 6, 2013, a 22-year-old Juan Francisco Estrada (26-2, 20 KOs) got a shot at the WBA (Unified) and WBO flyweight titles held by 32-year-old American boxer Brian Viloria (32-3, 19 KOs).
Estrada came in to the fight on a 1-fight losing streak with a 71% KO rate, and was fighting after a gap of 4 months and 20 days. Viloria was on a 6-fight win streak with a 54% KO rate, and fighting after a layoff of 4 months and 20 days.
Juan Francisco Estrada defeated Brian Viloria via split decision and wins the WBA (Unified) and WBO titles — in his first world-title fight. Estrada improves his record to 27-2, while Viloria adds a loss to his record at 32-4.
On September 26, 2015, the 25-year-old WBA (Unified) and WBO flyweight world champion, Juan Francisco Estrada (32-2, 23 KOs), faced Hernán Márquez, in a title defense fight.
Estrada came in to the fight on a 6-fight win streak with a 67% KO rate, and was fighting after a gap of 5 months and 29 days.
Juan Francisco Estrada stopped Hernán Márquez via TKO in the 10th round of the 12-round world-title fight, and successfully defended his WBA (Unified) and WBO flyweight titles. Estrada improves his record to 33-2 (24 KOs)
On April 26, 2014, the 24-year-old WBA (Unified) and WBO flyweight world champion, Juan Francisco Estrada (28-2, 20 KOs), faced Richie Mepranum, in a title defense fight.
Estrada came in to the fight on a 2-fight win streak with a 66% KO rate, and was fighting after a gap of 8 months and 30 days.
Juan Francisco Estrada stopped Richie Mepranum via TKO in the 10th round of the 12-round world-title fight, and successfully defended his WBA (Unified) and WBO flyweight titles. Estrada improves his record to 29-2 (21 KOs)
On October 23, 2020, Juan Francisco Estrada and Carlos Cuadras met again in a rematch.
Estrada came in to the fight on a 4-fight win streak with a 62% KO rate, and was fighting after a gap of 1 year, 1 month, and 29 days. Cuadras was on a 3-fight win streak with a 62% KO rate, and fighting after a layoff of 1 year, 1 month, and 9 days.
In the rematch, Juan Francisco Estrada stopped Carlos Cuadras via TKO in the 11th round of the 12-round world-title fight, and successfully defended his WBC and The Ring super-flyweight titles. Estrada improves his record to 41-3 (28 KOs), while Cuadras adds a loss to his record at 39-4-1.
On September 6, 2014, the 24-year-old WBA (Unified) and WBO flyweight world champion, Juan Francisco Estrada (29-2, 21 KOs), faced Giovani Segura, in a title defense fight.
Estrada came in to the fight on a 3-fight win streak with a 67% KO rate, and was fighting after a gap of 4 months and 11 days.
Juan Francisco Estrada stopped Giovani Segura via TKO in the 11th round of the 12-round world-title fight, and successfully defended his WBA (Unified) and WBO flyweight titles. Estrada improves his record to 30-2 (22 KOs)