Canelo Álvarez has three losses against three opponents on his boxing record. For a list of Álvarez's best fights, refer to "Best fights of Canelo Álvarez".
On September 13, 2025 Canelo Álvarez met Terence Crawford in a super-middleweight (WBA (Super), WBC, IBF, WBO, The Ring) world-title defense fight. Álvarez was 35 years old and with a record of 63-3-2 (39), and Crawford was 37 years old and with a record of 41-0 (31). Álvarez lost the fight via 12-round unanimous decision and lost the titles.
On May 7, 2022 Canelo Álvarez fought Dmitry Bivol in a light-heavyweight world-title fight for Bivol's WBA (Super) title. Álvarez was 31 years old and with a record of 57-2-2 (39), and Bivol was 31 years old and with a record of 19-0 (11). Álvarez lost the fight via 12-round unanimous decision.
On September 14, 2013 Canelo Álvarez, the WBC and The Ring champion, met Floyd Mayweather Jr., the WBA (Super) champion, in a super-welterweight world-title unification fight. Álvarez was 23 years old and with a record of 42-1-1 (30), and Mayweather Jr. was 36 years old and with a record of 44-0 (26). Álvarez lost the fight via 12-round majority decision and lost his titles.