On August 29, 2008, a 37-year-old Manuel Medina (67-15-1, 32 KOs) and Malcolm Klassen met in the ring.
Medina came in to the fight after a draw in his last fight with a 38% KO rate, and was fighting after a gap of 1 year, 1 month, and 24 days.
Manuel Medina lost to Malcolm Klassen via TKO in the 2nd round, and adds an loss to his record at 67-16-1.
On May 31, 2006, 35-year-old Manuel Medina (66-14, 32 KOs) and Cassius Baloyi fought for the vacant IBF super-featherweight title.
Medina came in to the fight on a 3-fight win streak with a 40% KO rate, and was fighting after a gap of 2 months and 7 days.
Manuel Medina was defending his super-featherweight titles and, fighting for the super-featherweight IBF titles against Cassius Baloyi and lost via TKO in the 11th round, and adds an loss to his record at 66-15.
On July 12, 2003, Manuel Medina and Scott Harrison met again in an immediate rematch.
Medina came in to the fight on a 3-fight win streak with a 39% KO rate, and was fighting after a gap of .
Manuel Medina was defending his featherweight WBO titles against Scott Harrison and lost via TKO in the 11th round, and adds an loss to his record at 63-14.
On February 1, 2003, 31-year-old Manuel Medina (60-12, 28 KOs) and 29-year-old Juan Manuel Márquez (39-2, 31 KOs) fought for the vacant IBF featherweight title.
Medina came in to the fight on a 1-fight losing streak with a 38% KO rate, and was fighting after a gap of 9 months and 5 days. Márquez was on a 10-fight win streak with a 75% KO rate, and fighting after a layoff of 7 months and 11 days.
Juan Manuel Márquez stopped Manuel Medina via TKO in the 7th round of the 12-round world-title fight. Márquez improves his record to 40-2 (32 KOs), while Medina adds a loss to his record at 60-13.
On April 27, 2002, the 31-year-old IBF featherweight world champion, Manuel Medina (60-11, 28 KOs), faced a 35-year-old American boxer Johnny Tapia (51-2-2, 28 KOs), in a title defense fight.
Medina came in to the fight on a 4-fight win streak with a 39% KO rate, and was fighting after a gap of 5 months and 11 days. Tapia was on a 3-fight win streak with a 50% KO rate, and fighting after a layoff of 3 months and 8 days.
Johnny Tapia defeated Manuel Medina via majority decision and wins the IBF title. Tapia improves his record to 52-2-2, while Medina adds a loss to his record at 60-12.
On November 13, 1999, the 28-year-old IBF featherweight world champion, Manuel Medina (56-10, 26 KOs), faced a 27-year-old British boxer Paul Ingle (21-1, 15 KOs), in a title defense fight.
Medina came in to the fight on a 3-fight win streak with a 39% KO rate, and was fighting after a gap of 6 months and 28 days. Ingle was on a -1-fight win streak with a 68% KO rate, and fighting after a layoff of 7 months and 3 days.
Paul Ingle defeated Manuel Medina via unanimous decision and wins the IBF title — in his first world-title fight. Ingle improves his record to 22-1, while Medina adds a loss to his record at 56-11.
On August 7, 1997, a 26-year-old Manuel Medina (53-9, 25 KOs) and Derrick Gainer met in the ring in a super-featherweight bout.
Medina came in to the fight on a 1-fight losing streak with a 40% KO rate, and was fighting after a gap of 2 months and 21 days.
Manuel Medina lost to Derrick Gainer via KO in the 9th round, and adds an loss to his record at 53-10.
On May 17, 1997, Manuel Medina and Luisito Espinosa met again in a rematch.
Medina came in to the fight on a 1-fight win streak with a 41% KO rate, and was fighting after a gap of 5 months and 1 day. Espinosa was on a 8-fight win streak with a 44% KO rate, and fighting after a layoff of 6 months and 15 days.
Luisito Espinosa defeated Manuel Medina via technical decision in the rematch and successfully defended his WBC featherweight title. Espinosa improves his record to 41-7, while Medina adds a loss to his record at 53-9.
On August 31, 1996, a 25-year-old Manuel Medina (52-7, 24 KOs) got a shot at the featherweight WBO title held by 22-year-old British boxer Naseem Hamed (22-0, 20 KOs).
Medina came in to the fight on a 1-fight win streak with a 40% KO rate, and was fighting after a gap of 4 months and 19 days. Hamed was on a 22-fight win streak with a 90% KO rate, and fighting after a layoff of 2 months and 23 days.
The challenger refused to continue the fight in the 11th round, and Naseem Hamed is crowned the new featherweight world champion. Hamed improves his record to 23-0 (21 KOs), while Medina adds a loss to his record at 52-8.
On December 11, 1995, the 24-year-old WBC featherweight world champion, Manuel Medina (51-6, 24 KOs), faced a 28-year-old Filipino boxer Luisito Espinosa (36-7, 19 KOs), in a title defense fight.
Medina came in to the fight on a 2-fight win streak with a 42% KO rate, and was fighting after a gap of 2 months and 18 days. Espinosa was on a 4-fight win streak with a 44% KO rate, and fighting after a layoff of 2 months and 2 days.
Luisito Espinosa defeated Manuel Medina via unanimous decision and wins the WBC title. Espinosa improves his record to 37-7, while Medina adds a loss to his record at 51-7.
On January 28, 1995, Manuel Medina and Tom Johnson met again in a rematch.
Medina came in to the fight on a 2-fight win streak with a 44% KO rate, and was fighting after a gap of 4 months and 2 days.
Manuel Medina was defending his featherweight titles and, fighting for the featherweight IBF titles against Tom Johnson and lost via unanimous decision in the 12-round featherweight fight, and adds an loss to his record at 49-6.
On June 26, 1993, a 22-year-old Manuel Medina (47-4, 23 KOs) got a shot at the super-featherweight IBF title held by 28-year-old Puerto Rican boxer John John Molina (31-3, 23 KOs).
Medina came in to the fight on a 1-fight win streak with a 45% KO rate, and was fighting after a gap of 1 month and 15 days. Molina was on a 10-fight win streak with a 67% KO rate, and fighting after a layoff of 1 month and 12 days.
John John Molina defeated Manuel Medina via unanimous decision and successfully defended his IBF super-featherweight title. Molina improves his record to 32-3, while Medina adds a loss to his record at 47-5.
On February 26, 1993, Manuel Medina and Tom Johnson met again in a rematch.
Medina came in to the fight on a 17-fight win streak with a 44% KO rate, and was fighting after a gap of 4 months and 3 days.
Manuel Medina was defending his featherweight IBF titles against Tom Johnson and lost via split decision in the 12-round featherweight fight, and adds an loss to his record at 46-4.
On July 10, 1989, an 18-year-old Manuel Medina (29-2, 15 KOs) and Juan Carlos Salazar met in the ring.
Medina came in to the fight on a 27-fight win streak with a 48% KO rate, and was fighting after a gap of 1 month and 19 days.
Manuel Medina lost to Juan Carlos Salazar via TKO in the 10th round, and adds an loss to his record at 29-3.
On January 16, 1986, a 14-year-old Manuel Medina (2-1, 0 KOs) and Alex Madrid met in the ring.
Medina came in to the fight on a 1-fight losing streak with a 0% KO rate, and was fighting after a gap of 1 month and 11 days.
Manuel Medina lost to Alex Madrid via TKO in the 4th round, and adds an loss to his record at 2-2.
On December 5, 1985, a 14-year-old Manuel Medina (2-0, 0 KOs) and Gerardo Martinez met in the ring.
Medina came in to the fight on a 2-fight win streak with a 0% KO rate, and was fighting after a gap of 25 days.
Manuel Medina lost to Gerardo Martinez via points decision in the 4-round fight, and adds an loss to his record at 2-1.