On November 16, 2001, Manuel Medina and Frank Toledo met again in a rematch.
Medina came in to the fight on a 3-fight win streak with a 38% KO rate, and was fighting after a gap of 6 months and 20 days.
In the rematch, Manuel Medina stopped the champion via TKO in the 5th round of the 12-round world-title fight, and is crowned the new IBF featherweight champion. Medina improves his record to 60-11 (28 KOs)
On July 22, 1992, the 21-year-old IBF featherweight world champion, Manuel Medina (43-3, 21 KOs), faced Fabrizio Cappai, in a title defense fight.
Medina came in to the fight on a 14-fight win streak with a 45% KO rate, and was fighting after a gap of 4 months and 8 days.
The challenger refused to continue the fight in the 10th round, and Manuel Medina is crowned the new featherweight world champion. Medina improves his record to 44-3 (22 KOs)
On April 24, 1998, a 27-year-old Manuel Medina (54-10, 26 KOs) got a shot at the IBF featherweight title held by Héctor Lizárraga.
Medina came in to the fight on a 1-fight win streak with a 40% KO rate, and was fighting after a gap of 6 months and 6 days.
Manuel Medina defeated Héctor Lizárraga via unanimous decision and wins the IBF title. Medina improves his record to 55-10
On August 12, 1991, a 20-year-old Manuel Medina (40-3, 21 KOs) got a shot at the IBF featherweight title held by Troy Dorsey.
Medina came in to the fight on a 11-fight win streak with a 48% KO rate, and was fighting after a gap of 2 months and 13 days.
Manuel Medina defeated Troy Dorsey via unanimous decision and wins the IBF title — in his first world-title fight. Medina improves his record to 41-3
On May 21, 1989, an 18-year-old Manuel Medina (28-2, 14 KOs) and Ashby Dancy met in the ring for the 2nd time,.
Medina came in to the fight on a 26-fight win streak with a 46% KO rate, and was fighting after a gap of .
In the rematch, Manuel Medina stopped Ashby Dancy via TKO in the 1st round. Medina improves his record to 29-2 (15 KOs)
On July 23, 2004, a 33-year-old Manuel Medina (63-14, 30 KOs) and Leonardo Resendiz met in the ring in a super-featherweight bout.
Medina came in to the fight on a 1-fight losing streak with a 39% KO rate, and was fighting after a gap of 1 year and 11 days.
Manuel Medina stopped Leonardo Resendiz via TKO in the 3rd round. Medina improves his record to 64-14 (31 KOs)
On October 23, 1992, the 21-year-old IBF featherweight world champion, Manuel Medina (45-3, 22 KOs), faced Moussa Sangare, in a title defense fight.
Medina came in to the fight on a 16-fight win streak with a 45% KO rate, and was fighting after a gap of 1 month and 11 days.
Manuel Medina defeated Moussa Sangare via majority decision and successfully defended his IBF featherweight title. Medina improves his record to 46-3
On July 12, 2003, a 32-year-old Manuel Medina (62-13, 30 KOs) got a shot at the WBO featherweight title held by Scott Harrison.
Medina came in to the fight on a 2-fight win streak with a 40% KO rate, and was fighting after a gap of 1 month and 6 days.
Manuel Medina defeated Scott Harrison via split decision and wins the WBO title. Medina improves his record to 63-13
On September 23, 1995, a 24-year-old Manuel Medina (50-6, 24 KOs) got a shot at the WBC featherweight title held by Alejandro González.
Medina came in to the fight on a 1-fight win streak with a 42% KO rate, and was fighting after a gap of 5 months and 8 days.
Manuel Medina defeated Alejandro González via split decision and wins the WBC title. Medina improves his record to 51-6
On March 14, 1992, the 20-year-old IBF featherweight world champion, Manuel Medina (42-3, 21 KOs), faced Fabrice Benichou, in a title defense fight.
Medina came in to the fight on a 13-fight win streak with a 46% KO rate, and was fighting after a gap of 3 months and 25 days.
Manuel Medina defeated Fabrice Benichou via split decision and successfully defended his IBF featherweight title. Medina improves his record to 43-3